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Tip the Scales: How to Prevent Contamination
Did you know that contamination may be quietly affecting your lab through your choice of filter pipette tips? Cross-contamination is a major issue during the handling and preparation of samples. This problem leaves scientists with the daunting task of taking preventive measures to ensure that the samples are protected from unwanted particles. By understanding the role of filter tips, the major contaminants and the importance of selecting high-performance tips, you can effectively reduce your risk.

Filter Tip 101
Filter tips play a crucial role in various laboratory experiments, including sensitive PCR procedures. They are specifically designed to block airborne particles or macromolecules that could contaminate the handled samples. The use of filter tips significantly minimizes the potential contamination of pipettor tip cones, preventing sample contamination and reducing the risk of false-positive results. However, filter tips are not created equal. USA Scientific utilizes proprietary technology in our filters to block more than 99% of aerosols due to our unique pore size matrix.

It's in the Air
Airborne particles and macromolecules are the primary sources of contamination in laboratory settings. These contaminants pose a significant risk to sensitive procedures like PCR, where DNA amplification occurs. Pipetting, a critical step in PCR sample preparation, is particularly vulnerable. Pipetting introduces air into the samples, increasing the possibility of contamination. When aerosolized particles containing contaminants such as unwanted DNA are not blocked during pipetting, experiment integrity is jeopardized. To address these issues, filter tips are used to prevent the entry of potential contaminants, ensuring reliable and accurate results in PCR experiments.

Put the Block on Contamination
Effective filter tips play a vital role in reducing contamination risks in experiments, particularly in sensitive PCR procedures. The blocking efficiency of a filter tip is crucial in preventing contamination and cross-contamination. Filter tips can effectively block particles from entering from the pipette into the sample, and vice versa. When selecting filter tips, it's essential to consider their blocking efficiency. Tips that block above 99% provide the highest level of protection against contamination, making them the preferred choice for reliable and accurate experiments.

Using high-blocking-efficiency filter tips significantly reduces the risk of cross- contamination and potential false-positive results. Implementing strong prevention standards, such as proper pipetting techniques, is also recommended to minimize aerosol generation. By prioritizing these measures, you can enhance the integrity and reproducibility of your research, affirming your commitment to accurate and reliable outcomes in the pursuit of scientific discoveries.
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